Senior/Principal Associate Scientist, Preclinical Research

Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. Compass’ scientific focus is on the relationship between angiogenesis, the immune system and tumor growth. The company pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. These include modulation of the microvasculature via angiogenesis-targeted agents, induction of a potent immune response via activators on effector cells in the tumor microenvironment, and alleviation of immunosuppressive mechanisms used by tumors to evade immune surveillance. Compass plans to advance its product candidates through clinical development as both standalone therapies and in combination with proprietary pipeline antibodies based on supportive clinical and nonclinical data. The company was founded in 2014 and is headquartered in Boston, Massachusetts. For more information, visit

Our dynamic team is growing. The Preclinical Research team is seeking a highly motivated, independent Senior or Principal Associate Scientist. The ideal candidate desires to be part of an energetic, fast-paced, and collaborative team, where there is opportunity for career growth.

Key Responsibilities:

  • Collaborate with colleagues and research leaders to ensure individual, team and departmental goals are achieved
  • Independently design, plan and execute cell-based functional assays using cell lines or primary human and NHP cells. These may include, but are not limited to, fluorescent/luminescent reporter assays, MLR, killing and phagocytosis assays for the purpose of screening antibody drug candidates
  • Independently design, plan and execute ELISA assays to assess antibody PK and ADA in mouse, NHP or human serum
  • Independently generate, analyze and interpret data; troubleshoot experiments and present results in team and departmental meetings
  • Maintain highly detailed and complete electronic notebook record of experiments
  • Contribute to the writing of scientific reports


  • BS or MS in immunology, cell biology, or a similar field
  • 6 or more years of laboratory experience, biotech/pharma experience required
  • Detail-oriented with a focus on robust technical replication and consistency
  • Demonstrated experience in multi-color flow cytometry, plate and cell-based assay development, cell culture; in vivo experimentation experience is a plus
  • Experience in working with primary human and non-human primate immune cells/tissues
  • Strong organizational and time-management skills, effective written and oral communication skills
  • Detail oriented and self-motivated, willing take on new challenges
  • Ability to work in a fast-paced environment and adjust quickly to changing priorities
  • Proficiency in Excel, GraphPad, FlowJo, PowerPoint and other Microsoft Suite Products
  • A strong desire to positively impact the lives of patients


At Compass Therapeutics, we provide employees with an inclusive offering of benefits and a competitive compensation package. We offer our employees competitive salaries, discretionary bonuses, and meaningful equity participation. Our benefits support the health and wellness of our employees; from medical, dental and vision benefits to health reimbursement arrangement, flexible spending accounts, sponsored gym membership, and an employee assistance program. We also provide company matched 401(k) and Roth 401(k) programs and other tools for financial wellness. Additional benefits include commuter reimbursement, subsidized parking, and substantial paid time off including a winter shut-down week.

We believe in growing and developing our team, and therefore, we invest in the development of strong values and culture. We are invested in employee success and provide tuition reimbursement, employee recognition programs and referral programs, training opportunities and maintain a comprehensive Performance Management cycle. While building a strong foundation, Compass culture can be seen every day in the form of curiosity, teamwork, passion, and cross functional collaboration.